Tag: biology · clear
115 items — page 4 of 5
Inheritance patterns of mitochondrial DNA in multi-generational maternal pedigrees: Insights from mitochondrial whole-genome sequencing
A ProbLog program to infer individual genotypes from familial phenotypes in autosomal, X-linked, and Y-linked Mendelian disorders
The automated reconstruction of patient family history is a common challenge in genetic counseling for disease prevention. Such a family history is usually determined for a particular subset of diseases that are Mendeli…
PN-QNN: Harnessing Physical Noise as a Native Regularizer in Photonic Hybrid Quantum Neural Networks
Physical noise in near-term quantum hardware is usually treated as a nuisance to suppress. We ask whether it can instead act as a hardware-native regularizer for photonic hybrid quantum-classical neural networks (PHQCNN…
EvoThink: Evolving Thinking in Large Reasoning Models via Self-Pruning and Aha-Moment Preference Optimization
Large Reasoning Models (LRMs) often suffer from overthinking due to redundant verification steps. Existing approaches for mitigating overthinking, such as fast-slow thinking switching and reasoning trajectory compressio…
DARWIN: Evolving Jailbreak Adversary and Guardrail for LLM Safety Evaluation and Protection
Most existing LLM safety evaluation and defense methods follow a static formulation: jailbreak vulnerabilities are evaluated with fixed attack methods, and guardrails are trained on fixed malicious prompt datasets. Howe…
The Amyloid Precursor Protein as a Universal Survival Molecule: A Critical Perspective on APP-Suppressing Therapies for Alzheimer's Disease
Abstract The amyloid precursor protein (APP) is best known in Alzheimer’s disease (AD) research as the source of the neurotoxic amyloid-β (Aβ) peptide. Consequently, therapeutic strategies now entering clinical trials s…
Belgian BAG
The Belgium BAG includes groups situated at four Flemish universities: Antwerpen, Brussels, Ghent and Leuven. The proposed projects are highly diverse, including viral, prokaryotic and eukaryotic proteins with a strong …
NORWAY BAG
The fifteen PIs associated to this proposal represent the entire crystallography community in Norway and are affiliated to the major Norwegian universities. The research interests of the PIs and their collaborators revo…
Probing α-carboxysome biogenesis and modularity with bacterial microcompartment counterparts
Bacterial microcompartments (BMCs) are protein-based organelles in prokaryotes that optimize metabolic pathways by confining specific enzymatic reactions within selectively permeable shells, playing critical roles in pr…
BAG Barcelona
BAG Barcelona is formed by 10 groups with a long tradition of accessing the ESRF. The groups belong to three different research institutions: the Institute of Molecular Biology of Barcelona from the Spanish Research Cou…
The Digital Workflow in Preclinical Practical Activity: Application in Paediatric Dentistry at the Mohammed VI Faculty of Dental Medicine UM6SS-A Satisfaction Survey.
The need for standardization and improved open (meta)data practices in metaproteomics.
Identifying the angiogenic receptor expression in mantle cell lymphoma patients and murine models.
Comparative assessment of large language models for microbial phenotype assignment.
The Metaproteomics Initiative: five years of community-driven progress.
Nesting biology of the primitively eusocial bee Augochlora phoemonoe (Halicitdae)
Building methodology for discovering and developing Chinese medicine based on network biology
Breeding Biology of Snakehead, Channa striatus (Bloch) from District Badin Sindh, Pakistan
Title Pending 23320
Title Pending 25432
Graph Learning on Ensembles of Cyclic Peptides: An Investigation of Molecular Ensemble Modeling
Molecular property prediction from structure often uses a single representative conformation, even though many molecules exist as conformational ensembles in solution. We introduce EnsembleEGNN, a molecular ensemble fou…
Local intercellular coupling is sufficient for long-range calcium signaling
Long-range intercellular calcium (Ca2+) signaling coordinates biological processes ranging from fertilization to contraction and cell death. The classical model attributes this long-range propagation to rapid diffusion …
From Berg-Purcell precision bounds to clock-limited information capacity
Physical limits to chemical sensing are traditionally expressed as Berg-Purcell bounds on estimation accuracy. Whether these bounds also limit the total amount of information a molecular receptor can transmit has remain…